2-Fluorophenyl isocyanate → HCID 21434594, compound

HRID 2398051Notes

Reaction equation

HRID 2398051 reaction equation
[CH3:1][O:2][C:3]1[N:8]=[C:7]([NH:9][CH:10]([CH3:12])[CH3:11])[N:6]=[C:5]([NH:13][CH2:14][CH2:15][OH:16])[N:4]=1.[F:17][C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[N:24]=[C:25]=[O:26]>C(N(CC)CC)C>[CH3:1][O:2][C:3]1[N:8]=[C:7]([NH:9][CH:10]([CH3:12])[CH3:11])[N:6]=[C:5]([NH:13][CH2:14][CH2:15][O:16][C:25](=[O:26])[NH:24][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][C:18]=2[F:17])[N:4]=1

Participants

4

Reactant 2

HCID 855882-Fluorophenyl isocyanateHCID 12937527HCID 12937527, compound

Product 1

HCID 21434594HCID 21434594, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineCatalyst

Procedure

A solution of 5 g of 2-methoxy-4-isopropylamino-6-(2-hydroxyethylamino)-s-triazine, 3.0 g o-fluorophenyl isocyanate and 10 drops triethylamine was stirred at 25° C. for about 2 days. The reaction mixture was filtered to give the product. The melting point and elemental analysis on the product are tabulated in Table I.

Workup

  1. filtrationThe reaction mixture was filtered
  2. customto give the product

Sources & evidence

ORD record
ord-e84674e7b4db4dc8bac006590d904294
Source dataset
uspto-grants-1977_05
Patent number
US04024141

Reaction notes

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