Methyl iodide → HCID 21434697, compound

Participants

Reaction Steps

One gram (0.00383 mole) of the compound of Example 1 is dissolved at 60° C. in 30 ml. of dimethylformamide, the resulting solution is brought to room temperature, then 0.2 g. of a 50% oily suspension of sodium hydride is added. After 1 hour, 0.25 ml. (0.004 mole) of methyl iodide is added and the obtained mixture is stirred for 5 hours and concentrated to dryness. The obtained residue is taken up with water and recrystallized from ethanol. Yield, 0.55 g., m.p., 144°-145° C.

Provenance & Evidence