Cyclohexyl isocyanate → HCID 68125090, compound

Participants

Reaction Steps

By the reaction of 3-ethylmethylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide with cyclohexylisocyanate in a manner analogous to that described in Example 1, there is obtained 1-[(3-ethylmethylcarbamoyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)sulfonyl]-3-cyclohexylurea. The starting material can be prepared by first reacting ethylmethylamine with phosgene to give ethylmethylcarbamoyl chloride and subsequently bringing the latter to reaction with 2,3,4,5-tetrahydro-1H-3-benzazepine-7-sulfonamide hydrochloride.

Provenance & Evidence