1,1-Bis(methylthio)-2-nitroethylene → HCID 70620345, compound

HRID 2398264Notes

Reaction equation

HRID 2398264 reaction equation
[OH:1][C:2]1[C:3]([CH2:8][S:9][CH2:10][CH2:11][NH2:12])=[N:4][CH:5]=[CH:6][CH:7]=1.[N+:13]([CH:16]=[C:17](SC)[S:18][CH3:19])([O-:15])=[O:14]>>[N+:13]([CH:16]=[C:17]([S:18][CH3:19])[NH:12][CH2:11][CH2:10][S:9][CH2:8][C:3]1[C:2]([OH:1])=[CH:7][CH:6]=[CH:5][N:4]=1)([O-:15])=[O:14]

Participants

3

Reactant 2

HCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 129515342-{[(2-Aminoethyl)sulfanyl]methyl}pyridin-3-ol

Product 1

HCID 70620345HCID 70620345, compound

Procedure

By the procedure of Example 4(i), 3-hydroxy-2-[(2-aminoethyl)- thiomethyl]pyridine (from the dihydrobromide (4.2 g)) is reacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) to give 1-nitro-2-methylthio-2-[2-((3-hydroxy-2-pyridyl)methylthio)-ethylamino]ethylene which, on reaction with methylamine by the process of Example 3(ii) gives 1-nitro-2-methylamino-2-[2-((3-hydroxy-2-pyridyl)methylthio)ethylamino]ethylene.

Sources & evidence

ORD record
ord-5fde007554ae49aa8f70ce628d91e641
Source dataset
uspto-grants-1977_05
Patent number
US04024260

Reaction notes

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