1,1-Bis(methylthio)-2-nitroethylene → HCID 70620345, compound

Participants

Reaction Steps

By the procedure of Example 4(i), 3-hydroxy-2-[(2-aminoethyl)- thiomethyl]pyridine (from the dihydrobromide (4.2 g)) is reacted with 1-nitro-2,2-bis-methylthioethylene (2.0 g) to give 1-nitro-2-methylthio-2-[2-((3-hydroxy-2-pyridyl)methylthio)-ethylamino]ethylene which, on reaction with methylamine by the process of Example 3(ii) gives 1-nitro-2-methylamino-2-[2-((3-hydroxy-2-pyridyl)methylthio)ethylamino]ethylene.

Provenance & Evidence