Hydrochloric Acid → HCID 12642573, compound

HRID 2398307Notes

Reaction equation

HRID 2398307 reaction equation
[Cl-].[Cl-].[Cl-].[Al+3].C([O:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)(=O)CCCCC.Cl>>[OH:12][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:18]=1[C:13](=[O:12])[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 522678Phenyl hexanoateHCID 6451240Aluminum(III) Chloride

Product 1

HCID 12642573HCID 12642573, compound

Conditions

Temperature
120 °C

Procedure

24 g (0.18 mole) of powdered aluminium trichloride were carefully added to 31 g (0.16 mole) of phenyl hexanoate and the mixture was slowly heated with occasional stirring to 120° C and was held there for 11/2 hours. The residue was ground into a powder and was poured into iced dilute hydrochloric acid with stirring. The mixture was extracted with ether and the ether extracts were washed with dilute sodium hydroxide solution, then with water, dried over magnesium sulfate and evaporated to dryness to obtain 14.2 of (1-(2'-hydroxyphenyl)-hexan-1one as a pale yellow oil. IR spectrum showed o-hydroxyphenylcarbonyl at 1650cm-1.

Workup

  1. temperaturethe mixture was slowly heated
  2. custom2 hours
  3. stirringwith stirring
  4. extractionThe mixture was extracted with ether
  5. washthe ether extracts were washed with dilute sodium hydroxide solution
  6. dry with materialwith water, dried over magnesium sulfate
  7. customevaporated to dryness

Sources & evidence

ORD record
ord-dc6d9248f6c84421a7f945dc116524d7
Source dataset
uspto-grants-1977_05
Patent number
US04024276

Reaction notes

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