Cysteamine → 3-[(2-Aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole

HRID 2398422Notes

Reaction equation

HRID 2398422 reaction equation
[Cl:1][C:2]1[S:6][N:5]=[C:4]([CH2:7]Cl)[N:3]=1.[NH2:9][CH2:10][CH2:11][SH:12]>>[NH2:9][CH2:10][CH2:11][S:12][CH2:7][C:4]1[N:3]=[C:2]([Cl:1])[S:6][N:5]=1

Participants

3

Reactant 2

HCID 6058CysteamineHCID 3326105-Chloro-3-(chloromethyl)-1,2,4-thiadiazole

Product 1

HCID 205674873-[(2-Aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole

Procedure

Reacting 5-chloro-3-chloromethyl-1,2,4-thiadiazole with cysteamine by the procedure of Example 1(i)(c) (c) gives 3-[(2-aminoethyl)thiomethyl]-5-chloro-1,2,4-thiadiazole.

Sources & evidence

ORD record
ord-f0c1cfe0f1b842f0b998324b4294ac29
Source dataset
uspto-grants-1977_05
Patent number
US04024271

Reaction notes

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