Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)- → (4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

HRID 2398441Notes

Reaction equation

HRID 2398441 reaction equation
C[O:2][C:3]1[CH:25]=[CH:24][C:6]([C:7]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][C:10]=2[C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[O:8])=[CH:5][CH:4]=1.Cl.N1C=CC=CC=1>>[OH:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([C:9]2[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=3[O:11][C:10]=2[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[O:8])=[CH:24][CH:25]=1

Participants

3

Reactant 2

HCID 6613416Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-HCID 10176127Pyridinium chloride

Product 1

HCID 13264991(4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

Procedure

3-(4-Methoxybenzoyl)-2-phenylbenzofuran (16.4 g., 0.05 mol.) is combined with 50 g. of freshly distilled pyridine hydrochloride and the mixture is refluxed one hour. The hot mixture is poured with stirring onto an ice-dilute hydrochloric acid mixture and the precipitate is collected to give 3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Workup

  1. additionThe hot mixture is poured
  2. customthe precipitate is collected

Sources & evidence

ORD record
ord-73a56a9b62f84a449736bfa1d50dd343
Source dataset
uspto-grants-1977_05
Patent number
US04024273

Reaction notes

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