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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2398441Generated: October 30, 2026

Methanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)- → (4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanone

https://huagongshe.com/reaction/2398441

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanone, (4-methoxyphenyl)(2-phenyl-3-benzofuranyl)-HCID 6613416—
ReactantPyridinium chlorideHCID 10176127—
Product(4-Hydroxyphenyl)(2-phenyl-1-benzofuran-3-yl)methanoneHCID 13264991—

Reaction Steps

3-(4-Methoxybenzoyl)-2-phenylbenzofuran (16.4 g., 0.05 mol.) is combined with 50 g. of freshly distilled pyridine hydrochloride and the mixture is refluxed one hour. The hot mixture is poured with stirring onto an ice-dilute hydrochloric acid mixture and the precipitate is collected to give 3-(4-hydroxybenzoyl)-2-phenylbenzofuran.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04024273
Source datasetuspto-grants-1977_05
ORD IDord-73a56a9b62f84a449736bfa1d50dd343
Source noteuspto-grants-1977_05