Benzoyl chloride → HCID 54469111, compound

Participants

Reaction Steps

6.5 g 2-amino-4-trifluoromethyl-5-fluoro-benzene sulfonamide are suspended in 150 ml dry benzene. 2.6 g benzoyl chloride are added to the vigorously stirred suspension, after which the reaction mixture is gently refluxed during 4 hours. The reaction mixture is then left aside overnight. The resulting white solid is then suction filtered and recrystallized from aqueous ethanol, to give 6.1 g 2-benzoylamino-4-trifluoromethyl-5-fluoro-benzene sulfonamide, m.p.= 223° C.

Provenance & Evidence