Phosphorus oxychloride → HCID 68119874, compound

Participants

Reaction Steps

The mixture of 0.3 g of N-(4-amino-o-tolyl)-4-carbamoylphthalamide, 2 ml of dioxane and 5 ml of phosphorus oxychloride is refluxed for 1 hour and evaporated. The residue is taken up in methylene chloride, the solution washed with cold aqueous sodium carbonate, dryed and evaporated, to yield the N-(4-amino-o-tolyl)-4-cyanophthalimide, which is identical with that obtained according to Example 20.

Provenance & Evidence