Acetic Acid → HCID 68118813, compound

HRID 2398572Notes

Reaction equation

HRID 2398572 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[O:10])[O:8][C:6](=O)[C:5]2=[CH:11][CH:12]=1.[NH2:13][C:14]1[CH:22]=C[C:17](C(O)=O)=[CH:16][C:15]=1[CH3:23].[C:24]([OH:27])(=[O:26])[CH3:25]>>[C:24]([C:25]1[CH:17]=[CH:16][C:15]([CH3:23])=[C:14]([N:13]2[C:9](=[O:10])[C:4]3=[CH:3][C:2]([Cl:1])=[CH:12][CH:11]=[C:5]3[C:6]2=[O:8])[CH:22]=1)([OH:27])=[O:26]

Participants

4

Reactant 3

HCID 176Acetic AcidHCID 670444-Chlorophthalic anhydrideHCID 755984-Amino-3-methylbenzoic acid

Product 1

HCID 68118813HCID 68118813, compound

Procedure

The starting material is prepared as follows: The suspension of 6.0 g of 4-chlorophthalic anhydride, 5.0 g of 4-amino-3-methylbenzoic acid and 75 ml of acetic acid is refluxed for 3 hours, cooled to room temperature, filtered and the residue washed with diethyl ethyl, to yield the N-(4-carboxy-o-tolyl)-4-chlorophthalimide melting at 250°-252°.

Workup

  1. customThe starting material is prepared
  2. temperatureis refluxed for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with diethyl ethyl

Sources & evidence

ORD record
ord-833f211144aa4967b44c6dd860757b69
Source dataset
uspto-grants-1977_05
Patent number
US04025505

Reaction notes

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