HCID 12452841, compound → 2-Methyl-5-(propan-2-yl)furan-3-carboxylic acid

HRID 2398655Notes

Reaction equation

HRID 2398655 reaction equation
[CH:1]([C:4]1[O:8][C:7]([CH3:9])=[C:6]([C:10]([O:12]CC)=[O:11])[CH:5]=1)([CH3:3])[CH3:2]>[OH-].[Na+]>[CH:1]([C:4]1[O:8][C:7]([CH3:9])=[C:6]([C:10]([OH:12])=[O:11])[CH:5]=1)([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 12452841HCID 12452841, compound

Product 1

HCID 214334052-Methyl-5-(propan-2-yl)furan-3-carboxylic acid

Reagents, catalysts & solvents 1

HCID 14798Sodium HydroxideSolvent

Procedure

Saponification of 0.5 g of the ester was accomplished by refluxing 4 hours in 10 ml of 25% aqueous sodium hydroxide. Acidification precipitated the crude acid, which was recrystallized from water-ethanol to give 5isopropyl-2-methyl-3-furoic acid as white needles, mp 88.5° C.

Workup

  1. customAcidification precipitated the crude acid, which
  2. customwas recrystallized from water-ethanol

Sources & evidence

ORD record
ord-b1a5232e58be4758b755d18eaec55a79
Source dataset
uspto-grants-1977_05
Patent number
US04025537

Reaction notes

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