HCID 12452845, compound → HCID 21433408, compound

HRID 2398663Notes

Reaction equation

HRID 2398663 reaction equation
[CH3:1][C:2]1[O:6][C:5]([CH2:7][CH2:8][CH3:9])=[C:4]([C:10]([O:12]CC)=[O:11])[CH:3]=1>[OH-].[Na+].C(O)C>[CH3:1][C:2]1[O:6][C:5]([CH2:7][CH2:8][CH3:9])=[C:4]([C:10]([OH:12])=[O:11])[CH:3]=1

Participants

4

Reactant 1

HCID 12452845HCID 12452845, compound

Product 1

HCID 21433408HCID 21433408, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 14798Sodium HydroxideSolvent

Procedure

Saponification of 0.5 g of the ester was carried out by refluxing 12 hours in 10 ml of 25% aqueous sodium hydroxide and 5 ml of ethanol. Acidification precipitated the crude acid which was purified by sublimination to give 5-methyl-2-propyl-3-furoic acid, mp 91°-102° C.

Workup

  1. customAcidification precipitated the crude acid which
  2. customwas purified by sublimination

Sources & evidence

ORD record
ord-a613d4d8ab324bd7859b0b067c6edd91
Source dataset
uspto-grants-1977_05
Patent number
US04025537

Reaction notes

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