Hydrochloric Acid → 1-(2-Aminoethyl)-5-(2,4-dinitrophenylthio)tetrazole hydrochloride

HRID 2398736Notes

Reaction equation

HRID 2398736 reaction equation
C([NH:4][CH2:5][CH2:6][N:7]1[C:11]([S:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:14]=2[N+:22]([O-:24])=[O:23])=[N:10][N:9]=[N:8]1)(=O)C.[ClH:25]>C(O)C>[ClH:25].[NH2:4][CH2:5][CH2:6][N:7]1[C:11]([S:12][C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][C:14]=2[N+:22]([O-:24])=[O:23])=[N:10][N:9]=[N:8]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 203828141-(2-Acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole

Product 1

HCID 203828111-(2-Aminoethyl)-5-(2,4-dinitrophenylthio)tetrazole hydrochloride

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of 6.5 g. (0.02 mol.) of 1-(2-acetamidoethyl)-5-(2,4-dinitrophenylthio)tetrazole, 100 ml. of 12 N hydrochloric acid and 100 ml. of 95% ethanol was refluxed for 4.5 hours. The mixture was evaporated to dryness to give a gummy residue which crystallized upon addition of ethanol to give 1-(2-aminoethyl)-5-(2,4-dinitrophenylthio)-tetrazole hydrochloride, m.p. 217°-219° (d).

Workup

  1. additionA mixture of 6.5 g
  2. customThe mixture was evaporated to dryness
  3. customto give a gummy residue which
  4. customcrystallized upon addition of ethanol

Sources & evidence

ORD record
ord-5d8f99df99014d5580368095b7e2f2d0
Source dataset
uspto-grants-1977_05
Patent number
US04025626

Reaction notes

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