Trifluoroacetic acid → HCID 178514099, compound

HRID 2398741Notes

Reaction equation

HRID 2398741 reaction equation
C([O:5][C:6]([C:8]1[N:13]2[C:14](=[O:28])[CH:15]([NH:16][C:17](=[O:27])[CH2:18][S:19]([CH2:22][C:23]([F:26])([F:25])[F:24])(=[O:21])=[O:20])[C@H:12]2[S:11][CH2:10][C:9]=1[CH:29]([S:36][C:37]1[NH:41][N:40]=[N:39][N:38]=1)[CH2:30][CH2:31][NH:32][C:33]([NH2:35])=[O:34])=[O:7])(C)(C)C.FC(F)(F)C(O)=O>C(#N)C>[F:25][C:23]([F:24])([F:26])[CH2:22][S:19]([CH2:18][C:17]([NH:16][CH:15]1[C:14](=[O:28])[N:13]2[C:8]([C:6]([OH:7])=[O:5])=[C:9]([CH:29]([S:36][C:37]3[NH:41][N:40]=[N:39][N:38]=3)[CH2:30][CH2:31][NH:32][C:33]([NH2:35])=[O:34])[CH2:10][S:11][C@H:12]12)=[O:27])(=[O:20])=[O:21]

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 1784506867-(2,2,2-Trifluoroethylsulfonylacetamido)-3-[1-(2-ureidoethyl)-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid t-butyl ester

Product 1

HCID 178514099HCID 178514099, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

The ester is dissolved in acetonitrile and trifluoroacetic acid is added. The solution is stirred for 3 hours, then evaporated to dryness to give the title compound.

Workup

  1. customevaporated to dryness

Sources & evidence

ORD record
ord-6e0226ba34c64910a3a4233b4a70174f
Source dataset
uspto-grants-1977_05
Patent number
US04025626

Reaction notes

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