Sodium Hydroxide → HCID 86734777, compound

Participants

Reaction Steps

Methyl 2-p-chlorophenyl-α-methoxy-6-benzoxazolyl-acetate (4.0 g.) was dissolved in dioxan (50 ml.) and a solution of sodium hydroxide (0.7g) in water was added. The solution was stirred for three hours then evaporated to dryness. The residue was stirred with dilute hydrochloric acid for thirty minutes. The solid was filtered off and recrystallised from water-ethanol to give 2-p-chlorophenyl-α-methoxy-6-benzoxazolylacetic acid, m.pt. 164°-6° C.

Provenance & Evidence