Hydrochloric Acid → HCID 178527129, compound

HRID 2398773Notes

Reaction equation

HRID 2398773 reaction equation
[NH:1]1[C:5]([C:6]2[CH:7]=[CH:8][C:9]3[C:10](=O)[C:11]4[C:16]([S:17](=[O:21])(=[O:20])[C:18]=3[CH:19]=2)=[CH:15][CH:14]=[CH:13][CH:12]=4)=[N:4][N:3]=[N:2]1.Cl>[Zn].C(O)(=O)C>[NH:1]1[C:5]([C:6]2[CH:7]=[CH:8][C:9]3[CH2:10][C:11]4[C:16]([S:17](=[O:21])(=[O:20])[C:18]=3[CH:19]=2)=[CH:15][CH:14]=[CH:13][CH:12]=4)=[N:4][N:3]=[N:2]1

Participants

5

Reactant 2

HCID 313Hydrochloric Acid2×HCID 178515054HCID 178515054, compound

Product 1

HCID 178527129HCID 178527129, compound

Reagents, catalysts & solvents 2

HCID 23994ZincCatalystHCID 176Acetic AcidSolvent

Procedure

To 3-(5-tetrazolyl)thioxanthone-10,10-dioxide (1.25g.), zinc wool (2.50g.) and mercuric acetate (0.10g.) was added acetic acid (25 ml.) and concentrated hydrochloric acid (25 ml.), and the mixture boiled under reflux for 2hr. After this time a further amount of hydrochloric acid (1.5ml.) was added and the mixture boiled for a further 4 hr., filtered while hot, cooled, the diluted with water. The crude product was filtered off, recrystallised three times from methanol, and dried at 80° C. in vacuo to give 3-(5-tetrazolyl)thioxanthene-10,10-dioxide m.pt. 233° C. with decomposition.

Workup

  1. temperatureunder reflux for 2hr
  2. filtration, filtered while hot,
  3. temperaturecooled
  4. additionthe diluted with water
  5. filtrationThe crude product was filtered off
  6. customrecrystallised three times from methanol
  7. customdried at 80° C. in vacuo

Sources & evidence

ORD record
ord-d6056b708f4249b1b4e5558e38b19b77
Source dataset
uspto-grants-1977_05
Patent number
US04025635

Reaction notes

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