Hydrogen Peroxide → HCID 12422797, compound

HRID 2398821Notes

Reaction equation

HRID 2398821 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[C:19]([CH3:20])=[C:15]([C:16]([OH:18])=[O:17])[C:14]([OH:21])=[C:13]([C:22]([CH3:25])([CH3:24])[CH3:23])[CH:12]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[OH:26]O.O>C(O)(=O)C>[N+:1]([C:4]1[CH:5]=[CH:6][C:7]([S:10]([C:11]2[C:19]([CH3:20])=[C:15]([C:16]([OH:18])=[O:17])[C:14]([OH:21])=[C:13]([C:22]([CH3:25])([CH3:24])[CH3:23])[CH:12]=2)=[O:26])=[CH:8][CH:9]=1)([O-:3])=[O:2]

Participants

5

Reactant 3

HCID 784Hydrogen PeroxideHCID 962WaterHCID 12422831HCID 12422831, compound

Product 1

HCID 12422797HCID 12422797, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

A solution of 5-(4-nitrophenylthio)-3-t-butyl-6-methylsalicylic acid (2.0 g.) in acetic acid (200 ml.) is mixed with 30% w/v aqueous hydrogen peroxide solution (11 ml.). The mixture is stirred at room temperature for 6 hours and then added to water (700 ml.). The precipitated solid thus formed is separated by filtration and crystallised from acetic acid to give 5-(4-nitrophenylsulphinyl)-3-t-butyl-6-methylsalicylic acid, m.p. 201°-202° C.

Workup

  1. customThe precipitated solid thus formed
  2. customis separated by filtration
  3. customcrystallised from acetic acid

Sources & evidence

ORD record
ord-911d452cdb9b48159d2e0fb5a11cf28b
Source dataset
uspto-grants-1977_05
Patent number
US04025647

Reaction notes

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