Hydrogen Peroxide → HCID 21434143, compound

HRID 2398822Notes

Reaction equation

HRID 2398822 reaction equation
[OH:1]O.[Cl:3][C:4]1[CH:34]=[C:33]([N+:35]([O-:37])=[O:36])[CH:32]=[CH:31][C:5]=1[NH:6][C:7](=[O:30])[C:8]1[C:9](=[C:11]([C:26]([CH3:29])([CH3:28])[CH3:27])[CH:12]=[C:13]([S:16][C:17]2[CH:22]=[C:21]([Cl:23])[C:20]([Cl:24])=[CH:19][C:18]=2[Cl:25])[C:14]=1[CH3:15])[OH:10]>C(O)(=O)C>[Cl:3][C:4]1[CH:34]=[C:33]([N+:35]([O-:37])=[O:36])[CH:32]=[CH:31][C:5]=1[NH:6][C:7](=[O:30])[C:8]1[C:9](=[C:11]([C:26]([CH3:29])([CH3:27])[CH3:28])[CH:12]=[C:13]([S:16]([C:17]2[CH:22]=[C:21]([Cl:23])[C:20]([Cl:24])=[CH:19][C:18]=2[Cl:25])=[O:1])[C:14]=1[CH3:15])[OH:10]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 21434129HCID 21434129, compound

Product 1

HCID 21434143HCID 21434143, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

30% w/v Aqueous hydrogen peroxide solution (1.5 ml.) is added to a solution of 2'-chloro-4'-nitro-5-(2,4,5-trichlorophenylthio)-3-t-butyl-6-methylsalicylanilide (0.4 g.) in acetic acid (15 ml.) at 50°-60° C. The mixture is heated at 95°-100° C. for 30 minutes and is then poured into ice cold water (200 ml.). The precipitated solid thus obtained is crystallised twice from acetic acid to give 2'-chloro-4'-nitro-5-(2,4,5-trichlorophenylsulphinyl)-3-t-butyl-6-methylsalicylanilide, m.p. 245°-246° C.

Workup

  1. temperatureThe mixture is heated at 95°-100° C. for 30 minutes
  2. customThe precipitated solid thus obtained
  3. customis crystallised twice from acetic acid

Sources & evidence

ORD record
ord-f4dbd89a088743eea8d62b22166c416d
Source dataset
uspto-grants-1977_05
Patent number
US04025647

Reaction notes

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