Hydrochloric Acid → HCID 178424809, compound

HRID 2398838Notes

Reaction equation

HRID 2398838 reaction equation
[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10]([NH:12][C:13]([NH:15]C(C)(C)C)=[O:14])=[NH:11].[ClH:20]>>[ClH:20].[CH3:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([CH3:8])[C:3]=1[NH:9][C:10]([NH:12][C:13]([NH2:15])=[O:14])=[NH:11]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 178424810HCID 178424810, compound

Product 1

HCID 178424809HCID 178424809, compound

Procedure

A mixture of 25.7 g. (0.106 moles) of 1-(2,6-dimethylphenylamidino)-3-(t-butyl)urea and 200 ml. of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, the solid filtered and washed with 10 ml. of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanol-ether to obtain (2,6-dimethylphenylamidino)urea hydrochloride.

Workup

  1. additionA mixture of 25.7 g
  2. temperatureThe reaction mixture is cooled
  3. filtrationthe solid filtered
  4. washwashed with 10 ml
  5. dry with materialof 1:1 HCl/H2O and dried
  6. customThe product is then recrystallized from ethanol-ether

Sources & evidence

ORD record
ord-77f2ced873d24a30840928b87b864c1d
Source dataset
uspto-grants-1977_05
Patent number
US04025652

Reaction notes

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