HRID2398876

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：CCCCCc1cc(O)c2c(c1)OC(C)(C)C1=C2CN(Cc2ccccc2)CC1

HCID21418117

未命名化合物

HCID70565727

未命名化合物

PRODUCTS

生成物

结构：CCCCCc1cc(OC(=O)CCCN2CCCCC2C)c2c(c1)OC(C)(C)C1=C2CN(Cc2ccccc2)CC1.Cl

HCID21418136

未命名化合物

PROCEDURE

实验过程

2-Benzyl-5,5-dimethyl-10-hydroxy-8-(1-pentyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine, γ-(2-methylpiperidino)- butyric acid hydrochloride and dicyclohexylcarbodiimide in equimolar amounts are reacted as in Example 1 to give the desired product.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-164a33a65303400ca4724770b860b410
来源数据集: uspto-grants-1977_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04025630
来源说明: uspto-grants-1977_05

反应 SMILES

[CH2:1]([N:8]1[CH2:13][C:12]2[C:14]3[C:23]([OH:24])=[CH:22][C:21]([CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:20][C:15]=3[O:16][C:17]([CH3:19])([CH3:18])[C:11]=2[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[ClH:30].[CH3:31][CH:32]1[CH2:37][CH2:36][CH2:35][CH2:34][N:33]1[CH2:38][CH2:39][CH2:40][C:41](O)=[O:42].C1(N=C=NC2CCCCC2)CCCCC1>>[ClH:30].[CH2:1]([N:8]1[CH2:13][C:12]2[C:14]3[C:23]([O:24][C:41](=[O:42])[CH2:40][CH2:39][CH2:38][N:33]4[CH2:34][CH2:35][CH2:36][CH2:37][CH:32]4[CH3:31])=[CH:22][C:21]([CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])=[CH:20][C:15]=3[O:16][C:17]([CH3:19])([CH3:18])[C:11]=2[CH2:10][CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1