HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → 2-Benzyl-5,5-dimethyl-10-[4-(2-methylpiperidino)butyryloxy]-8-(1-pentyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | 2-Benzyl-5,5-dimethyl-10-hydroxy-8-(1-pentyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine | HCID 21418117 | — |
| Reactant | 4-(2-Methylpiperidin-1-yl)butanoic acid hydrochloride | HCID 70565727 | — |
| Product | 2-Benzyl-5,5-dimethyl-10-[4-(2-methylpiperidino)butyryloxy]-8-(1-pentyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine hydrochloride | HCID 21418136 | — |
Reaction Steps
2-Benzyl-5,5-dimethyl-10-hydroxy-8-(1-pentyl)-1,2,3,4-tetrahydro-5H-[1]benzopyrano[3,4-d]pyridine, γ-(2-methylpiperidino)- butyric acid hydrochloride and dicyclohexylcarbodiimide in equimolar amounts are reacted as in Example 1 to give the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04025630 |
| Source dataset | uspto-grants-1977_05 |
| ORD ID | ord-164a33a65303400ca4724770b860b410 |
| Source note | uspto-grants-1977_05 |