2-Thiophenecarboxylic acid, tetrahydro-3-oxo-, methyl ester → 7-(3-cyclopropyl-2-propyl)-1,2-dihydro9-hydroxy-4-oxo-4H-thieno[2,3-c][1]benzopyran

HRID 2398901Notes

Reaction equation

HRID 2398901 reaction equation
O=[C:2]1[CH2:6][CH2:5][S:4][CH:3]1[C:7]([O:9][CH3:10])=[O:8].[CH:11]1([CH2:14][CH:15]([C:17]2[CH:18]=C(O)[CH:20]=[C:21]([CH:23]=2)[OH:22])[CH3:16])[CH2:13][CH2:12]1>>[CH:11]1([CH2:14][CH:15]([C:17]2[CH:23]=[C:21]([OH:22])[C:20]3[C:2]4[CH2:6][CH2:5][S:4][C:3]=4[C:7](=[O:8])[O:9][C:10]=3[CH:18]=2)[CH3:16])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 1028702-Thiophenecarboxylic acid, tetrahydro-3-oxo-, methyl esterHCID 538434965-(3-Cyclopropyl-2-propyl)resorcinol

Product 1

HCID 214338707-(3-cyclopropyl-2-propyl)-1,2-dihydro9-hydroxy-4-oxo-4H-thieno[2,3-c][1]benzopyran

Procedure

Following a procedure similar to that described in Example 1B hereinabove, methyl 3-oxo-2,3,4,5-tetrahydrothiophene-2-carboxylate is reacted with 5-(3-cyclopropyl-2-propyl)resorcinol to give 7-(3-cyclopropyl-2-propyl)-1,2-dihydro-9-hydroxy-4-oxo-4H-thieno[2,3-c][1]benzopyran.

Sources & evidence

ORD record
ord-a934d346eeb74814bf8aca10ecb3c493
Source dataset
uspto-grants-1977_05
Patent number
US04025630

Reaction notes

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