6-(4'-Amino-3'-nitro-phenyl)-4,5-dihydro-3(2H)-pyridazinone → 6-(3',4'-Diamino-phenyl)-4,5-dihydro-3(2H)-pyridazinone

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Reaction Steps

4.68 gm of 6-(4'-amino-3'-nitro-phenyl)-4,5-dihydro-3(2H)-pyridazinone werehydrogenated in 500 ml of ethanol at 40° C. for 4 hours in the presence of 1 gm of platinum dioxide at 5 atmospheres. Thereafter, the solution was cooled and filtered, and the filter cake was boiled with a mixture of 4 parts of isopropanol and 1 part of water. The resulting mixture was filtered, and upon cooling, the desired product crystallized out of the filtrate; m.p. 226° C.

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