HCID 54540911, compound → HCID 53670218, compound

HRID 2398939Notes

Reaction equation

HRID 2398939 reaction equation
[CH3:1][O:2][C:3](=[O:23])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:19])[CH:16]([CH3:18])[CH3:17])=[C:10]([N+:20]([O-])=O)[CH:9]=1)=[O:7]>C(O)C>[CH3:1][O:2][C:3](=[O:23])[CH2:4][CH2:5][C:6]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:19])[CH:16]([CH3:17])[CH3:18])=[C:10]([NH2:20])[CH:9]=1)=[O:7]

Participants

3

Reactant 1

HCID 54540911HCID 54540911, compound

Product 1

HCID 53670218HCID 53670218, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

15.5 gm of 4-(3'-nitro-4'-isobutyrylamino-phenyl)-4-oxo-butyric acid methylester were hydrogenated with 4 gm of palladized coal in 480 ml of ethanol at room temperature and 5 atmospheres pressure. The mixture was then suction-filtered, the filter cake was taken up in hot ethanol, the mixturewas filtered, and the reaction product was allowed to crystallize out of the filtrate; m.p. 178° C.

Workup

  1. filtrationThe mixture was then suction-filtered
  2. filtrationthe mixturewas filtered
  3. customto crystallize out of the filtrate

Sources & evidence

ORD record
ord-e8017ad7512148b2898662d932fbd3f9
Source dataset
uspto-grants-1977_05
Patent number
US04026891

Reaction notes

Loading…