Nitrobenzene → HCID 178481318, compound

HRID 2398996Notes

Reaction equation

HRID 2398996 reaction equation
[N+](C1C=CC=CC=1)([O-])=O.Cl.[CH3:11][N:12]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][N:14]=[C:13]1[C:20]([NH:22][NH:23][C:24](=[NH:26])[NH2:25])=N>>[NH2:25][C:24]1[NH:26][C:20]([C:13]2[N:12]([CH3:11])[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][N:14]=2)=[N:22][N:23]=1

Participants

3

Reactant 2

HCID 7416NitrobenzeneHCID 178478928HCID 178478928, compound

Product 1

HCID 178481318HCID 178481318, compound

Procedure

In 110 ml. of nitrobenzene, 7.6 g. (0.029 mole) of 2-(1-methyl-5-nitro-2-imidazolecarboximidoyl)-1-amidinohydrazine hydrocloride is stirred at reflux temperature for 23/4 hours, cooled, and the solid collected. This solid is washed with ethyl alcohol, ether, and air-dried to give 6 g. of the title compound, melting point 278°-280° (dec.). The product is purified by removing soluble impurities in a Soxhlet extractor with 95% ethanol. The insoluble products melts at 297°-299° (dec.).

Workup

  1. temperatureat reflux temperature for 23/4 hours
  2. temperaturecooled
  3. customthe solid collected
  4. washThis solid is washed with ethyl alcohol, ether
  5. customair-dried
  6. customto give 6 g

Sources & evidence

ORD record
ord-bdb44415abae4710b4483d644e1329e8
Source dataset
uspto-grants-1977_05
Patent number
US04026903

Reaction notes

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