反应详情

A 21.44 g. (0.10 mol) portion of (±)-2,6,10-trimethylundecan-1-ol was stirred and heated to 140° C. as HBr gas was bubbled through the liquid for 4.0 hr. The two-phase mixture was cooled, diluted with petroleum ether (B.P. 30°-60° C.) and washed with H2O, saturated aqueous NaHCO3 solution and brine. The solution was filtered through 100 g of Woelm neutral alumina III, stripped of solvent, and distilled to give (±)-1-bromo-2,6,10-trimethylundecane as a colorless liquid: bp 97°-99° C./0.10 mmHg.

1. customwas bubbled through the liquid for 4.0 hr
2. temperatureThe two-phase mixture was cooled
3. additiondiluted with petroleum ether (B.P. 30°-60° C.)
4. washwashed with H2O, saturated aqueous NaHCO3 solution and brine
5. filtrationThe solution was filtered through 100 g of Woelm neutral alumina III
6. distillationdistilled