Ammonia → HCID 21432748, compound

HRID 2399114Notes

Reaction equation

HRID 2399114 reaction equation
[CH2:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[N:8][C:7]([C:13](Cl)=[O:14])=[CH:6]2)[CH3:2].[NH3:16]>>[CH2:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[N:8][C:7]([C:13]([NH2:16])=[O:14])=[CH:6]2)[CH3:2]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 21432745HCID 21432745, compound

Product 1

HCID 21432748HCID 21432748, compound

Procedure

Aqueous ammonia solution (specific gravity 0.88; 10 ml.) was added to 6-ethylcinnolin-3-yl carbonyl chloride (1 g.). The resulting suspension was stirred overnight at room temperature. The resulting mixture was filtered and the solid residue was crystallised from aqueous ethanol to give 6-ethylcinnolin-3-ylcarboxamide, m.p. 215°-216° C.

Workup

  1. filtrationThe resulting mixture was filtered
  2. customthe solid residue was crystallised from aqueous ethanol

Sources & evidence

ORD record
ord-992a5d13ff0241138a45b3795c3d8cbd
Source dataset
uspto-grants-1977_05
Patent number
US04027023

Reaction notes

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