Ethylene Glycol → HCID 21432757, compound
Reaction equation
Cl[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1.[Na].[CH2:10]([OH:13])[CH2:11][OH:12]>>[OH:12][CH2:11][CH2:10][O:13][CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][N:4]=1Participants
4
Procedure
2-Chloromethylpyridine is reacted with the sodium salt of ethylene glycol to give 2-(2-hydroxyethoxymethylpyridine. Treatment of 2-(2-hydroxyethoxymethyl)pyridine with thionyl chloride gives 2-(2-chloroethoxymethyl)pyridine.
Sources & evidence
- ORD record
- ord-46baff5d515e4088a5c6ceb9c7bc5086
- Source dataset
- uspto-grants-1977_05
- Patent number
- US04027026
Reaction notes
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