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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2399124Generated: October 30, 2026

Benzoyl isothiocyanate → N-benzoyl-N'-[2-(2-pyridylmethylthio)ethyl]thiourea

https://huagongshe.com/reaction/2399124

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl isothiocyanateHCID 68284—
Reactant2-((2-Aminoethyl)thiomethyl)pyridineHCID 12889401—
SolventChloroformHCID 6212—
ProductN-benzoyl-N'-[2-(2-pyridylmethylthio)ethyl]thioureaHCID 21432770—

Reaction Steps

A solution of 2-[(2-aminoethyl)thiomethyl]pyridine (6.0 g.) and benzoyl isothiocyanate (6.0 g.) in chloroform (150 ml.) is heated under reflux for one hour and concentrated to give N-benzoyl-N'-[2-(2-pyridylmethylthio)ethyl]thiourea.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04027026
Source datasetuspto-grants-1977_05
ORD IDord-9c902716b6544b7cb1f56d26aadafa88
Source noteuspto-grants-1977_05