HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 19385508, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | alpha,alpha'-Dichloro-p-xylene | HCID 12171 | — |
| Reactant | 1-[2-(Propan-2-yloxy)phenyl]piperazine | HCID 10944016 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19385508 | HCID 19385508 | — |
Reaction Steps
A solution of α,α'-dichoro-p-xylene(30.40 g ,0.174 mol), N-[2-(1-methylethoxy)phenyl]piperazine (12.70 g, 0.058 mol), triethylamine (6.08 g, 0.06 mol), and THF (200 mL) was refluxed for 4 h. Ether (100 mL) and 1N HCl (100 mL) were added producing a white suspension which was filtered to give 4-[[1-[2-(1-methylethoxy)phenyl]-4-piperazinyl]methyl]benzyl chloride hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05449677 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-97e14bf1f93b4bd9b3c8042064712c8b |
| Source note | uspto-grants-1995_09 |