Hydrochloric Acid → HCID 67619063, compound

Participants

Reaction Steps

To a suspension of 2.20 g (6.14 mmol) of cis-3-t-butoxycarbonylamino-4-methyl-1-(1-methylindazol-3-ylcarbonyl)pyrrolidine in 22 ml of ethanol was added 11 ml of ethanol saturated with hydrogen chloride at room temperature, and then the mixture was stirred for 3 hours at room temperature. After completion of the reaction, solvent was distilled off and resultant residue was crystallized with addition of dioxane to give 1.81 g (quantitative) of aimed compound. m.p. 177°-180° C.

Provenance & Evidence