Methylamine → HCID 54559287, compound

HRID 2399581Notes

Reaction equation

HRID 2399581 reaction equation
[CH3:1][O:2][N:3]=[C:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]#[CH:16])[C:5](OC)=[O:6].[CH3:17][NH2:18]>>[CH3:1][O:2][N:3]=[C:4]([C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[C:15]#[CH:16])[C:5]([NH:18][CH3:17])=[O:6]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 53785538HCID 53785538, compound

Product 1

HCID 54559287HCID 54559287, compound

Procedure

1 g (4.6 mmol) of the acetylene compound prepared in Example 1 is added to 20 ml of a 40% strength methylamine solution, and the mixture is stirred for 45 minutes at 40°-50° C. The solution is extracted with methyl tert-butyl ether, dried and evaporated down. 700 mg (70%) of the compound remain as a colorless solid.

Workup

  1. extractionThe solution is extracted with methyl tert-butyl ether
  2. customdried
  3. customevaporated down

Sources & evidence

ORD record
ord-ceb287f31d884d378843a15d3894a731
Source dataset
uspto-grants-1995_09
Patent number
US05449809

Reaction notes

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