HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trityl chloride → HCID 19384400, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trityl chloride | HCID 6456 | — |
| Reactant | 1-Aminocyclopentanemethanol | HCID 66307 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 19384400 | HCID 19384400 | — |
Reaction Steps
A mixture of 1-amino-1-cyclopentanemethanol (3.00 g; 26.05 mmol) and triphenylmethylchloride (7.26 g; 26.05 mmol) in 70 ml CH2Cl2 is heated overnight. The reaction mixture is cooled and flash chromatographed twice using 5:1; hexane:EtOAc to obtain 1-hydroxymethyl-1-triphenylmethylaminocyclopentane as a thick yellow oil which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05451596 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-cd87fbc3700947f98178f282e5f01614 |
| Source note | uspto-grants-1995_09 |