反应详情

A mixture of 4-(benzoxazol-2-yl)benzyl bromide (0.6 g; 2.08 mmol) and triphenylphosphine (0.55 g; 2.08 mmol) in 40 ml benzene is refluxed for 48 hrs. The reaction mixture is cooled, the white solid which precipitates is filtered off, dried under vacuum to get 4-(benzoxazol-2-yl)benzyltriphenylphosphonium bromide and used directly in the next step.

1. temperatureis refluxed for 48 hrs
2. temperatureThe reaction mixture is cooled
3. customthe white solid which precipitates
4. filtrationis filtered off
5. customdried under vacuum