Triphenylphosphine → HCID 19384397, compound

HRID 2399744Notes

Reaction equation

HRID 2399744 reaction equation
[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]1[CH:17]=[CH:16][C:13]([CH2:14][Br:15])=[CH:12][CH:11]=1.[C:18]1([P:24]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>C1C=CC=CC=1>[Br-:15].[O:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[C:10]1[CH:17]=[CH:16][C:13]([CH2:14][P+:24]([C:25]2[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=2)([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)[C:18]2[CH:19]=[CH:20][CH:21]=[CH:22][CH:23]=2)=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 11776TriphenylphosphineHCID 110335154-(Benzoxazol-2-yl)benzyl bromide

Product 1

HCID 19384397HCID 19384397, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

A mixture of 4-(benzoxazol-2-yl)benzyl bromide (0.6 g; 2.08 mmol) and triphenylphosphine (0.55 g; 2.08 mmol) in 40 ml benzene is refluxed for 48 hrs. The reaction mixture is cooled, the white solid which precipitates is filtered off, dried under vacuum to get 4-(benzoxazol-2-yl)benzyltriphenylphosphonium bromide and used directly in the next step.

Workup

  1. temperatureis refluxed for 48 hrs
  2. temperatureThe reaction mixture is cooled
  3. customthe white solid which precipitates
  4. filtrationis filtered off
  5. customdried under vacuum

Sources & evidence

ORD record
ord-b0601a569d624f359ab52e522fe2cd3d
Source dataset
uspto-grants-1995_09
Patent number
US05451596

Reaction notes

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