HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → trans-2-Amino-cycloheptanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 8-Oxabicyclo(5.1.0)octane | HCID 67512 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | trans-2-Amino-cycloheptanol | HCID 12886914 | — |
Reaction Steps
In a sealed tube, cycloheptene oxide (5.44 g; 48.50 mmol)and ammonium hydroxide solution (10 ml) in 4 ml methanol is heated to 80° C. for 72 hrs. After removal of the heat, the mixture is concentrated in vacuo to obtain trans-2-aminocycloheptanol which is used directly in the next step.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05451596 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-5560e5cdb8df4130a5dcb78d0f7550b2 |
| Source note | uspto-grants-1995_09 |