1-Bromooctane → HCID 19384555, compound

HRID 2399785Notes

Reaction equation

[CH3:1][C:2]1([CH3:17])[CH2:16][C:6]2[C:7]3[CH:13]=[CH:12][C:11]([C:14]#[N:15])=[CH:10][C:8]=3[NH:9][C:5]=2[CH2:4][CH2:3]1.Br[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26]>>[CH3:1][C:2]1([CH3:17])[CH:16]([CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH3:26])[C:6]2[C:7]3[CH:13]=[CH:12][C:11]([C:14]#[N:15])=[CH:10][C:8]=3[NH:9][C:5]=2[CH2:4][CH2:3]1

Participants

Reactant 2

HCID 81401-Bromooctane

HCID 19384482HCID 19384482, compound

Product 1

HCID 19384555HCID 19384555, compoundYield 108.3%

Procedure

Using the procedure of Example 9, 5.6 g of the carbonitrile from Example 5 was alkylated with 6.35 g of 1-bromooctane to give 9.1 g (96.4%) of 5,6,7,8-tetrahydro-8,8-dimethyl-9-octyl-9H-dibenzo[b,d]pyrrole-3-carbonitrile as a yellow oil. This material was used without purification.

Sources & evidence

ORD record: ord-59410934f5054b1fbca92b4cbcce9aff
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05451600

Reaction notes

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