Butyl bromide → HCID 19384535, compound

HRID 2399797Notes

Reaction equation

[C:1]1([CH2:7][O:8][C:9]2[CH:10]=[CH:11][CH2:12][C:13]3[C:17]=2[N:16]=[C:15]2[CH2:18][CH2:19][CH2:20][CH2:21][C:14]=32)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[CH2:23][CH2:24][CH2:25][CH3:26]>>[C:1]1([CH2:7][O:8][C:9]2[CH:10]=[CH:11][CH:12]([CH2:23][CH2:24][CH2:25][CH3:26])[C:13]3[C:17]=2[N:16]=[C:15]2[CH2:18][CH2:19][CH2:20][CH2:21][C:14]=32)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 8002Butyl bromide

HCID 19384476HCID 19384476, compound

Product 1

HCID 19384535HCID 19384535, compoundYield 88.2%

Procedure

Using the procedure of Example 9, the alkylation of 5.0 g. of 1,2,3,4-tetrahydro-6-phenylmethoxy-9H-dibenzo[b,d]pyrrole from Example 56 was reacted with 1-bromobutane (2.68 g) to give 5.3 g (88.2%) of 1,2,3,4-tetrahydro-6-phenylmethoxy-9-butyl-9H-dibenzo[b,d]pyrrole as a yellow oil after chromatographic purification.

Sources & evidence

ORD record: ord-55cafcb579714d9fb2640891dfa8a23f
Source dataset: uspto-grants-1995_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05451600

Reaction notes

Loading…