HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromooctane → 4-(Octyloxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromooctane | HCID 8140 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 2-Hydroxybenzonitrile | HCID 11907 | — |
| Solvent | Methyl Ethyl Ketone | HCID 6569 | — |
| Product | 4-(Octyloxy)benzonitrile | HCID 145161 | — |
Reaction Steps
To a solution of cyanophenol (25 g) and potassium carbonate (50 g) in 2-butanone (320 ml) was added bromooctane (61 ml) at room temperature. The stirred mixture was heated under reflux until TLC revealed complete reaction, i.e. about 48 hr. The mixture was filtered, after which the solvent and excess alkyl bromide were removed in vacuo to give a colorless liquid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05453218 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-04efbb17f2be49eaab39480d6c7fc4f4 |
| Source note | uspto-grants-1995_09 |