Bromoacetyl bromide → HCID 19382371, compound

HRID 2400050Notes

Reaction equation

HRID 2400050 reaction equation
[NH2:1][C:2]1[O:3][CH:4]=[CH:5][C:6]=1[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1.[Br:15][CH2:16][C:17](Br)=[O:18].BrCC(NC1C=COC=1C(=O)C1C=CC=CC=1)=O>>[Br:15][CH2:16][C:17]([NH:1][C:2]1[O:3][CH:4]=[CH:5][C:6]=1[C:7](=[O:14])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)=[O:18]

Participants

4

Reactant 3

HCID 61147Bromoacetyl bromideHCID 19382363HCID 19382363, compoundHCID 19382370HCID 19382370, compound2×

Product 1

HCID 19382371HCID 19382371, compound

Procedure

2-Amino-3-benzoylfuran may be acylated with bromoacetyl bromide using the procedure for compound 7. When compound 6 is replaced in this procedure with compound 29 the title structure is obtained.

Workup

  1. customis obtained

Sources & evidence

ORD record
ord-1504314846064ac7a100ad3cf8b48c6b
Source dataset
uspto-grants-1995_09
Patent number
US05453424

Reaction notes

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