HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-((Dimethylamino)methyl)-4-piperidinol dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 19382159 | HCID 19382159 | — |
| Product | 4-((Dimethylamino)methyl)-4-piperidinol dihydrochloride | HCID 19382216 | — |
Reaction Steps
4.5 g (19.4 mmol) of ethyl 4-dimethylaminomethyl-4-hydroxypiperidine-1-carboxylate are heated overnight under reflux with 35 ml of concentrated hydrochloric acid. The product is concentrated, and the crystals are triturated with acetone, filtered off with suction and dried in a vacuum desiccator over P4O10.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05453422 |
| Source dataset | uspto-grants-1995_09 |
| ORD ID | ord-706161d1ccac428bbbe9cfaae2ef2e21 |
| Source note | uspto-grants-1995_09 |