Gamma-Butyrolactone → Gamma-Butyrolactone

HRID 2400148Notes

Reaction equation

HRID 2400148 reaction equation
[C:1]1(=[O:6])[O:5][CH2:4][CH2:3][CH2:2]1.[C:7](=O)(OC)OC.CN(C)CC>>[CH3:7][CH:2]1[CH2:3][CH2:4][O:5][C:1]1=[O:6].[C:1]1(=[O:6])[O:5][CH2:4][CH2:3][CH2:2]1

Participants

5

Reactant 3

HCID 7302Gamma-ButyrolactoneHCID 11723DimethylethylamineHCID 12021Dimethyl Carbonate

Product 2

HCID 7302Gamma-ButyrolactoneHCID 98323alpha-Methylbutyrolactone

Conditions

Temperature
200 °C

Procedure

A mixture of 21.5 g (250 mmol) of gamma-butyrolactone, 45 g (500 mmol) of dimethyl carbonate and 0.93 g (12.5 mmol) of dimethylethylamine was heated to 200° C. in an autoclave and stirred at this temperature for 5 hours. After cooling, 13.3 g (53%) of 2-methylbutyrolactone (selectivity 74%) and 6 g of unreacted gamma-butyrolactone were obtained by quantitative gas-chromatographic analysis of the discharged reaction mixture.

Workup

  1. temperatureAfter cooling

Sources & evidence

ORD record
ord-16baec6b538c4c138f29c67faa1fc50f
Source dataset
uspto-grants-1995_09
Patent number
US05453516

Reaction notes

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