HuagongsheHuagongshe Chemistry Print Report · For research reference only
4,6-Dichloropyrimidine → HCID 86669124, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4,6-Dichloropyrimidine | HCID 70943 | — |
| Reactant | N-BOC-ethylenediamine | HCID 187201 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86669124 | HCID 86669124 | — |
Reaction Steps
To 4,6-dichloropyrimidine (0.533 g, 35.8 mmol) in MeOH (15 ml) was added tert-butyl N-(2-aminoethyl)carbamate and the reaction stirred at room temperature for 6.5 hours. Reaction concentrated in vacuo, solids triturated with EtOAc/petrol. Filtrate which contains the desired product was concentrated and EtOAc and sat. NaHCO3 added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796244B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-1455d12ba553437cbde309095ab95212 |
| Source note | uspto-grants-2014_08 |