Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400348Generated: October 31, 2026

Hydrochloric Acid → HCID 68163058, compound

https://huagongshe.com/reaction/2400348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantHCID 68162667HCID 68162667—
SolventEthanolHCID 702—
ProductHCID 68163058HCID 6816305818.2%

Reaction Conditions

Temperature60 °C

Reaction Steps

2-[2-(3-{3-[3-(2,2,2-Trifluoro-ethyl)-ureido]-phenyl}-imidazo[1,2-a]pyridin-7-yl)-pyrimidin-4-yl]-imidazole-1-sulfonic acid dimethylamide (140 mg, 0.23 mmol) dissolved in EtOH (5 ml) and MeOH(1 ml) treated with 2M HCl (1 ml) heated at 60° C. for 2 hours. Reaction mixture concentrated under reduced pressure and was purified by preparative HPLC to give product (20 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796244B2
Source datasetuspto-grants-2014_08
ORD IDord-c45f3ff67eef47bdb1560de2383da1ca
Source noteuspto-grants-2014_08