Hydrochloric Acid → HCID 67027545, compound

Participants

Reaction Steps

To 1-{3-[7-(2-Methyl-6-{4-[2-(tetrahydro-pyran-2-yloxy)-ethyl]-piperazin-1-yl}-pyrimidin-4-yl)-imidazo[1,2-a]pyridin-3-yl]-phenyl}-3-(2,2,2-trifluoro-ethyl)-urea (150 mg) treated with saturated HCl in EtOAc, reaction stirred RT for 1 hour, precipitated solid filtered and washed with EtOAc. The crude product was purified by preparative HPLC twice to give product (30 mg).

Provenance & Evidence