HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 123988195, compound → HCID 90228697, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 123988195 | HCID 123988195 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 90228697 | HCID 90228697 | 100.2% |
Reaction Steps
To a solution of compound 275 (400 mg, 0.86 mmol) in 30 mL of MeOH was added 0.8 g of Pd/C (10%, wet). The mixture was hydrogenated at room temperature for 2 h. The catalyst was removed by filtration through a celite pad. The filtrate was concentrated to afford compound 276 as a colorless gum (320 mg, 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796257B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-05e4e6e8f2e94c03a34d40bf8dd07428 |
| Source note | uspto-grants-2014_08 |