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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400748Generated: October 31, 2026

HCID 123988195, compound → HCID 90228697, compound

https://huagongshe.com/reaction/2400748

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 123988195HCID 123988195—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 90228697HCID 90228697100.2%

Reaction Steps

To a solution of compound 275 (400 mg, 0.86 mmol) in 30 mL of MeOH was added 0.8 g of Pd/C (10%, wet). The mixture was hydrogenated at room temperature for 2 h. The catalyst was removed by filtration through a celite pad. The filtrate was concentrated to afford compound 276 as a colorless gum (320 mg, 99%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796257B2
Source datasetuspto-grants-2014_08
ORD IDord-05e4e6e8f2e94c03a34d40bf8dd07428
Source noteuspto-grants-2014_08