HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131731727, compound → HCID 90228699, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131731727 | HCID 131731727 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 90228699 | HCID 90228699 | 83% |
Reaction Steps
To a solution of compound 286 (0.22 g, 0.44 mmol) in 10 mL of CH3OH was added 0.1 g of Pd—C (10%, wet). The mixture was hydrogenated at room temperature for 16 h. The catalyst was removed by filtration through a pad of celite. The filtrate was concentrated to afford compound 287 as a solid (0.15 g, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08796257B2 |
| Source dataset | uspto-grants-2014_08 |
| ORD ID | ord-99da7805437d40f687a8703b223d5950 |
| Source note | uspto-grants-2014_08 |