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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2400882Generated: November 1, 2026

1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehyde → HCID 86659642, compound

https://huagongshe.com/reaction/2400882

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2,4-Bis-trifluoromethyl-benzyl)-1H-indazole-5-carbaldehydeHCID 86654538—
ReactantHCID 86659643HCID 86659643—
ProductHCID 86659642HCID 86659642—

Reaction Steps

(5Z)-5-({1-[2,4-Bis(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[trans-3-fluoropiperidin-4-yl]-1,3-thiazolidine-2,4-dione was prepared from [2,4-bis(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 6) and 1,1-dimethylethyl trans-4-(2,4-dioxo-1,3-thiazolidin-3-yl)-3-fluoropiperidine-1-carboxylate (from Example 273) following General Procedure F.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08796256B2
Source datasetuspto-grants-2014_08
ORD IDord-dbdf59c5e6884bcca9a1048e6914c3eb
Source noteuspto-grants-2014_08