HRID2400889

反应详情

EQUATION

反应方程式

REACTANTS

反应物

反应SMILES：O=Cc1ccc2c(cnn2Cc2ccc(F)cc2C(F)(F)F)c1

HCID86654587

未命名化合物

反应SMILES：CC(C)(C)OC(=O)N1CC[C@@H](O)[C@H](N2C(=O)CSC2=O)C1

HCID86659650

未命名化合物

PRODUCTS

产物

$反应SMILES：O=C1S/C(=C\c2ccc3c(cnn3Cc3ccc(F)cc3C(F)(F)F)c2)C(=O)N1[C@@H]1CNCC[C@H]1O$

HCID86659652

未命名化合物

PROCEDURE

实验过程

(5Z)-5-({1-[4-Fluoro-2-(trifluoromethyl)benzyl]-1H-indazol-5-yl}methylidene)-3-[trans-4-hydroxypiperidin-3-yl]-1,3-thiazolidine-2,4-dione was prepared from [4-fluoro-2-(trifluoromethyl)benzyl]-1H-indazol-5-carbaldehyde (from Example 5) and 1,1-dimethylethyl trans-3-(2,4-dioxo-1,3-thiazolidin-3-yl)-4-hydroxy-piperidine-1-carboxylate (from Example 270) following General Procedure F.